Testosterone-based hormone therapy is medicine that can be used as part of your gender transition process. Some of the changes may be permanent while others may be reversible and go away when medication is stopped.
| Effect | Expected Onset | Expected Maximum Effect | Reversibility |
| Facial and Body Hair Growth | 1-6 months | 1-2 years | Permanent |
| Increased Muscle Mass and Strength | 6-12 months *significantly dependent on amount and type of exercise | 2-5 years | Reversible |
| Deepened Voice | 3-12 months | 1-2 years | Permanent |
| Cessation of Menstrual Periods | 2-6 months | N/A | Reversible |
| Clitoral Enlargement | 3-6 months | 1-2 years | Permanent |
| Body Fat Redistribution | 3-6 months | 2-5 years | Reversible |
| Skin Oiliness/ Acne | 1-6 months | 1-2 years | Reversible |
| Male Pattern Baldness | >12 months | Variable | Permanent |
| Increased Sex Drive | Variable | Variable | Reversible |