Detecting abnormalities in a Pap smear may be difficult because:
Abnormalities may not be picked up on the spatula or brush.
Abnormalities may be difficult to see.
Cytologists (those who study the cells) and clinicians are very careful about interpreting Pap tests and recommending follow-up care. They don't want to overlook anything unusual. They are also aware that failure to detect early cancers can lead to serious and even deadly consequences. Their caution may lead them to request re-doing the Pap test, or doing other tests. In some cases, the cytologist is unsure about whether or not there are precancerous changes. In such a case, your clinician will recommend repeat testing or other tests to be more sure.
As with mammography, fewer cancers are overlooked with these precautions. But having more tests done can lead to more anxiety, as well as expense. It is reassuring that these precautions improve the chance of finding abnormal cell changes as early as possible.
